翻訳と辞書 Words near each other ・ Death domain ・ Death Domain database ・ Death Domination ・ Death drive ・ Death Drive (album) ・ Death Drives Through ・ Death Drug ・ Death Drums Along the River ・ Death du Jour ・ Death Duel ・ Death Duel (video game) ・ Death Duel of Kung Fu ・ Death during consensual sex ・ Death Eater ・ Death education ・ Death effector domain ・ Death Equinox ・ Death erection ・ Death Erotica ・ Death Faces ・ Death Fiend ・ Death Flies East ・ Death flights ・ Death fold ・ Death Folder ・ Death for Life ・ Death for Sale ・ Death from a Distance ・ Death from a Top Hat ・ Death From Above Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Death effector domain ： ウィキペディア英語版 Death effector domain The death-effector domain (DED) is a protein interaction domain found to regulate a variety of cellular signalling pathways. The DED domain is found in inactive procaspases (cysteine proteases) and proteins that regulate caspase activation in the apoptosis cascade such as FAS-associating death domain-containing protein (FADD). FADD recruits procaspase 8 and procaspase 10 into a death induced signaling complex (DISC). This recruitment is mediated by a homotypic interaction between the procaspase DED and a second DED that is death effector domain in an adaptor protein that is directly associated with activated TNF receptors. Complex formation allows proteolytic activation of procaspase into the active caspase form which results in the initiation of apoptosis (cell death). Structurally the DED domain are a subclass of protein motif known as the death fold and contains 6 alpha helices, that closely resemble the structure of the Death domain. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Death effector domain」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.